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Home E-Weekly May 7, 2013

Researchers Consider Alternative Weight-Loss Surgery

Published: May 6, 2013

Working with laboratory rats and an experimental procedure, investigators have developed what may be a less-invasive alternative to gastric bypass surgery.

As reported online in the journal Endocrinology, the use of a catheter that diverts bile from its duct into the small intestine seems to produce weight-loss effects similar to those of bariatric surgeries.

"This may lead to novel ways to treat obesity related conditions," says Rohit Kohli, MBBS, MS, of the Cincinnati Children's Hospital Medical Center, the study's lead investigator. "Our results provide compelling evidence that manipulation of bile acids is sufficient to recreate the key effects of bariatric procedures, including gastric bypass, and may be especially beneficial to people with obesity related liver dysfunction."

While further studies are required, the researchers say their ultimate goal is the development of a procedure through which patients can reap the benefits of a gastric bypass while sidestepping the risks of surgery and the rearrangement of the GI tract.

David Bernard

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