A study appearing in the July issue of the journal Anesthesiology suggests that patients can inherit post-operative nausea and vomiting.
Previous studies had established family history as a risk factor, but this study is among the first to analyze a possible connection between PONV and such genetic factors as a family history of the condition, as well as motion sickness, migraine headaches and other adverse side effects of anesthesia.
Researchers from Penn State College of Medicine gathered DNA samples from and interviewed 122 patients who'd suffered PONV on at least 3 separate occasions following surgery.
Their findings revealed 41 genetic markers, known as single nucleotide polymorphisms (SNP), that may contribute to a patient's predisposition to PONV. Additionally, researchers discovered at least one SNP common to the patients with severe PONV.
The study's authors hope their research leads to the development of pre-operative tests for patients showing PONV risks, and a possible drug therapy for the complication.
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