CDC Announces Propofol Recall

Teva Pharmaceutical Industries is voluntarily recalling 2 lots of 100 ml vials of propofol — lots 31305429B and 31305430B — that tested positive for elevated levels of endotoxin. All clinicians are advised to stop using these lots of Teva-produced propofol as the manufacturer, the Centers for Disease Control and Prevention and the Food and Drug Administration investigate a potential link between the drug and recent febrile reactions among patients undergoing endoscopy. An initial investigation of these patients revealed that all had received propofol from vials manufactured by Teva, and FDA tests revealed high levels of endotoxin in the 2 lots being recalled, says the CDC. All patients have recovered from the adverse reaction.